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2 Beds
1 Bath
2,195 sqft

$319,000

25365 US HIGHWAY 281 S, SANANTONIO TX, 78264

Price per sqft$145.33
Built in1990
Property size2,195 sqft
Property typeResidential

Overview

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Listed Jul 14, 2026

Updated 2 days ago

Rare opportunity to own nearly 5 acres in the heart of South San Antonio's booming manufacturing and logistics corridor. Whether you're an entrepreneur, contractor, owner-operator, or simply dreaming of building a custom home with room for your business, this versatile 4.752-acre property offers the flexibility that's becoming increasingly difficult to find. All utilities in place and 2 houses to live in while you build. Best part, finance as residential but buy it for the land! in placeCreate a private residence with space for a workshop, oversized garage, equipment storage, RV or trailer parking, or a home-based business while enjoying the convenience of quick access to US Highway 281, Loop 1604, and I-35. Located just minutes from major employers including Toyota Motor Manufacturing, the South Side industrial corridor, distribution centers, healthcare facilities, and Texas A&M University-San Antonio, this property is ideally positioned for businesses that support manufacturing, construction, transportation, or service industries. The existing structures are not considered habitable and are being sold AS IS, with the primary value in the land. Mature native trees provide privacy and a beautiful setting for your future home while leaving plenty of room to expand your business, add a warehouse, workshop, office, or additional storage (subject to applicable zoning and permitting requirements). Whether you're looking to eliminate a daily commute, operate your business from home, or invest in one of San Antonio's fastest-growing commercial and industrial corridors, this property offers exceptional potential with the space to grow.

$2,122/mo

Est. mortgage payment based on a $319,000 home price.

All estimates are provided by Luxury Presence for informational purposes only. Actual amounts may vary.

Additional information

MLS® ID
2000318

Interior Features

Bedrooms
2
Bathrooms
1
Fireplace
Yes
Cooling
Yes
Heating
Yes
Basement
No

Exterior Features

Lot Size
4.75 Acres

Other Property Details

Taxes
$4,810
Tax Frequency
Annually
MLS provider logo

Courtesy of Celia Taylor, Option One Real Estate

Listing Contact: (210) 389-5266

Source:  ©2026 Local Expertise Regional Access

The data relating to real estate for sale on this website comes in part from the Internet Data exchange (IDX) program of the Local Expertise Regional Access®. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Real estate listings held by brokerage firms other than , are indicated by detailed information about them such as the name of the listing firms. Information deemed reliable but not guaranteed. The MLS may, at its discretion, require use of other disclaimers as necessary to protect participants and/or the MLS from liability. Copyright © [[year] Local Expertise Regional Access®. All Rights Reserved.

Data last updated 1:16 AM UTC, 10/6/2026

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